Drug Discovery- Lead scientist

Drug Discovery- Lead scientist

8-14 years
Not Specified

Job Description

Job description :
Educational Qualification: PhD in organic chemistry / medicinal chemistry
Experience: 9-12 Years (post PhD exempting any Post Doc/ teaching exp)
Job Purpose:
The purpose of the role is to lead the medicinal chemistry efforts supporting integrated drug discovery (IDD) projects for our clients working in a matrix organization.
Key Responsibilities:

  • Analyze SAR and be a part of team designing the next set of compounds ensuring that the project deliverables are met within the pre-defined timeline.
  • Part of the IDD core team working with the biologists DMPK scientists in-vivo pharmacologists CADD scientists and toxicologists to define the critical path and design the key experiments to arrive at the Go-No Go decisions for the projects.
  • Work with the chemistry leads within discovery chemistry to ensure that the design of the synthetic chemistry routes and execution the synthesis of target compounds is achieved flawlessly.
  • Liaise with the Functional Lead Medicinal Chemistry on project priorities and ensure that project deliverables are met.
  • Provide regular updates on project progress to the Research Director - medicinal chemistry / Functional Leads and clients.
  • Ensure resource allocation data integrity and adherence to safety in the work place for the team.
  • Ensure the implementation of regulatory and safety compliances.
  • Unwavering focus on the discovery and development novel therapeutics that improve the lives of people suffering from serious diseases
  • Exceptional creativity and innovation in the genuine spirit of collaboration
  • Core commitment to safety integrity compliance quality and service
  • Ensuring safety of self teams and lab/plant by adhering to safety protocols and following environment health and safety (EHS) requirements at all times in the workplace.
  • Ensuring that there are no safety non-compliances in areas that my team operates in.
  • Ensuring all assigned mandatory trainings related to data integrity health and safety measures are completed on time by all members of the team including self
  • Reporting incidents (or near-misses) and learnings from those incidents to avoid recurrence.
Technical/functional Skills:

  • Candidate should have a PhD in organic / medicinal chemistry from one of the reputed universities in India / abroad with a minimum of 9 -12 yrs. experience working in Integrated Drug Discovery (IDD) projects.
  • Excellent understanding of the concepts of drug discovery preferably having prior experience of progressing projects at least from hit identification to lead optimization
  • Has prior experience working in a cross-functional team comprising assay biologists DMPK scientists computational chemist and safety pharmacologists
  • Familiarity with molecular modelling concepts and tools is desirable
  • Evidence of having a strong scientific capability
  • Knowledge of route scouting
  • Robust knowledge for process safety and hazard evaluation
  • Strong Client communication skills


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