Being the headquarters of Khammam district and Khammam mandal, there are various jobs in Khammam. Khammam is one of the major educational hubs in the state. It has many premium pharmacy, MBA and engineering colleges. Some of them are Swarna Bharathi Institute of Science and Technology, Mamata Medical College, SR & BGNR Degree and KMDC Degree & PG College. These educational institutes have generated number of lecturer jobs, research jobs, lab technician jobs, administrator jobs and management jobs in Khammam.
The city is well connected by means of roadways and railways with all the major towns of the state. There are national and state highways passing through the city which has created number of employment opportunities in Khammam with respect to logistics, trade and cargo services.